120). Similarly, high IL-10 levels was found to be a prognostic factor in peripheral T cell lymphoma, which can lead to worsening of overall survival, low complete response rate, and higher early relapse rate (Ref. 122). Moreover, elevated IL-10 at diagnosis was found to be an independent prognostic marker in adult hemophagocytic lymphohistiocytosis patients in order to find the right treatment strategy (Ref. 123). This evidence concerns the gene IL10 and hemophagocytic syndrome.