NFKB1 and neoplasm: Nonetheless, the interplay between Wnt and NF-κB signaling pathways has attracted attention due to its regulatory role in inflammation-associated events such as cell proliferation, apoptosis, tumor differentiation, and migration.79–81 Moreover, the NF-κB pathway is intricately linked to the progression and prognosis of organ I/R injury.360–363 Recent studies have shed light on the crosstalk between Wnt and NF-κB signaling in processes like apoptosis, inflammation, oxidative stress, and fibrosis following ischemic heart injury and liver I/R injury.