Previously associated with epilepsy in clinical cohorts [7, 76, 77], the region harbors NDE1 [MIM: 609449], a gene associated with autosomal recessive lissencephaly [MIM: 614019] and microhydranencephaly [MIM: 605013] and whose mutation has been linked to epilepsy [78, 79]. This evidence concerns the gene NDE1 and NDE1-related microhydranencephaly.