CYP4V2 and Blindness: For instance, association between 4q35 CNVs and corneal conditions (chr4:186,687,554–187,182,384; ORU-shape = 18.2; 95%-CI [5.2; 63.1]; p = 5.0 × 10−6) mapped to CYP4V2 [MIM: 608614], a gene associated with autosomal recessive Bietti crystalline corneoretinal dystrophy [MIM: 210370], a disorder that impairs vision and progresses to blindness by age 50–60 years [59].