Inside the PD1-positive CD4 T groups, effector memory, effector naïve, and follicular helper CD4 T cells (Tfh) were found to be detrimental to cHL survival, whereas activated effector CD4 T cells, both naïve and total, were F. Polarized CD4 T cells encompass another important compartment that influences the outcome in cHL, and several of its components had already been studied. The gene discussed is CD4; the disease is classic Hodgkin lymphoma.