Overall, the mutation profile of the MYC/BCL2/BCL6-TH group is very similar to that of the MYC/BCL2-DH group (Fig. 3A), characterised by frequent mutations in follicular lymphoma associated genes (BCL2, CREBBP, KMT2D, EZH2, TNFRSF14). This evidence concerns the gene BCL2 and follicular lymphoma.