TUBB1 and pulmonary arterial hypertension: Of the 29 tested associations (7–12 for each of three CpG/TADs), the CpG marker (cg04917472) near the TSS of CTSZ showed the most marked (strongest effect) associations with CTSZ itself (β/SE = −0.27 +/− 0.0001 per Transcripts Per Million/TPM, p = 0.0167, Fig. 4A) and TUBB1 (β/SE = 0.15 +/− 0.0001 per TPM, p = 0.0124) expression levels in PAH (Supplementary Data 6).