Moreover, compared to those without prediabetes, individuals with prediabetes exhibited elevated BMI, SBP, DBP, FPG, ALT, AST, Scr, BUN, TC, TG, LDL-C, LCI, AIP, non-HDL- C, AC, CRI-I, CRI-II, RC, RC/HDL-C ratio, METS-IR, and CDRS levels, alongside lower HDL-C levels (all P < 0.05). This evidence concerns the gene GPT and prediabetes syndrome.