PCNT and Alzheimer disease: To further understand the potential mechanisms in KEN‐induced ADAM10 translation, we assessed differentially regulated genes (DEGs) by RNA‐seq in SH‐SY5Y‐APP cells, in which Aβ is overproduced thus remodeling amyloidogenesis in AD‐like pathology.[26, 33] Co‐expression networks were built to find relations among genes in the absence and presence of KEN (Figure S1, Supporting Information).