For example, higher levels of creatine phosphokinase, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) after ICI therapy initiation correlate well with greater risk of ICI-induced myocarditis (27), and cardiac troponin and natriuretic peptides are frequently elevated when ICI-induced myocarditis is diagnosed (28). The gene discussed is GPT; the disease is myocarditis.