As a key regulator of EMT and EndMT, DPP4 may contribute to DKD by promoting kidney fibrosis via suppressing SIRT3, FGFR1 and glucocorticoid receptor which are widely investigated anti-EMT and Anti-EndMT molecules [4, 8, 12, 41–45]. The gene discussed is FGFR1; the disease is diabetic kidney disease.