A similar increase in TLR2 and p-p65 expression was detected in primary Mettl3 cKO BMDM during 0 ~ 36 h post-infection with M. pneumoniae (Appendix Fig. S12B) and during 0–24 h post-infection with S. aureus (Appendix Fig. S12C). Here, METTL3 is linked to infection.