To identify the prognostic value of these LRLs in colon cancer, we performed univariate COX regression analysis on differentially expressed lncRNAs, and the result showed that 10 lncRNAs were closely corrected with overall survival of patients with colon cancer (AC093849.2, AC093849.2, AC104530.1, TSPEAR-AS1, AC138207.5, LINC01857, LINC02381, AL354836.1, PCED1B-AS1 and TNFRSF10A-AS1, threshold: p < 0.05) (Fig. 3B). The gene discussed is TSPEAR; the disease is malignant colon neoplasm.