INS and kidney disorder: Based on the results of the multiple regression model; duration of diabetes more than 10 years, insulin therapy, male sex, addiction to other drugs, family history of diabetes, higher body mass index, having non-proliferative retinopathy, nephropathy, history of heart or kidney disease, higher level of LDL cholesterol, HDL cholesterol, triglyceride (TG), significantly increase the chance of occurrence of diabetic foot ulcer.