It was also revealed in a study that miRNA-223-3p promotes apoptosis and inhibits proliferation of human hepatocellular carcinoma cells (hep3B) by regulating NLRP3, and miR-233 represses the proliferation of HCC cells and promotes apoptosis by directly targeting NLRP3 [44]. The gene discussed is NLRP3; the disease is hepatocellular carcinoma.