Dai et al. [41], found that the folk remedy Shuang Hua Tang (SHD) had an inhibitory effect on HCC by a mechanism that exerted an anticancer effect by activating ROS-mediated NLRP3 inflammasomes and repressing the NF-kB signaling route in liver cancer cells [42]. Here, NLRP3 is linked to hepatocellular carcinoma.