Importantly, no change in response to anti-PD1 was observed in vivo (Figure S8B) and all positive effects of IFN-induced Ly6Ehi neutrophils on T cells and T cell-mediated tumor killing were retained regardless of Ly6E status (Figures S8C–S8G)—suggesting that Ly6E has no functional role in the mechanism of response, but rather serves solely, in our study, as means to assay this subpopulation of neutrophil. This evidence concerns the gene IFNA1 and neoplasm.