KANSL1 and Alzheimer disease: In our results, we found blood mQTLs for AD and brain mQTLs for AD and PD to be associated with increased expression of KAT8; this is in contrast to gene expression in some of the same tissues, such as blood and brain mQTLs, for KANSL1. The associated increased expression of KAT8 in our results suggests that an increase in expression may be correlated with excess autophagy resulting in cell death, which is a hallmark symptom of all three NDDs (AD, PD, and LBD).56