Although it was reported high prevalence of atrio-ventricular block as the initial symptom[3] and ventricular tachycardia[42] of cardiac sarcoidosis, as the majority of cases were asymptomatic, periodic examinations such as electrocardiography, NT-proBNP appear to be effective in the early detection of cardiac sarcoidosis. The gene discussed is NPPB; the disease is cardiac sarcoidosis.