Similarly, increased levels of adhesion molecules in circulating CD4+ T cells (CCR8, CD18; Supplementary Fig. S5B) and monocytes (CD18, CCR8, Cd49f, CD54, LFA-3, P-selectin, CD29; Supplementary Fig. S5C) were observed in baseline samples from patients whose tumor had pCR compared with those that did not have pCR. This evidence concerns the gene CCR8 and neoplasm.