Pathwayanalysis of the final brain and serum 1X panels indicated overlappingof the adipocytokine signaling, AGE-RAGE signaling, alpha-linoleicacid metabolism, autophagy, arachidonic acid metabolism, choline metabolism,ether lipid metabolism, glycerophospholipid metabolism, ferroptosisinsulin resistance, Leishmaniasis, linoleic acid metabolism, necroptosis,neurotrophin signaling, retrograde endocannabinoid signaling, andsphingolipid signaling pathways. This evidence concerns the gene BDNF and leishmaniasis.