MAF and COVID-19: With regard to inflamed lung tissues, BALF cells obtained from patients with severe COVID-19 were shown to have upregulated expression of not only the genes encoding crucial cues accounting for Th2 cell “polarization” (GATA3, IL4R, and MAF) but also did not differ in production levels of key Th2 cytokines when assessing patients with varying degrees of COVID-19 severity (151).