The results of the univariate Cox regression analysis showed that Tumor length (HR=1.284, 95% CI: 1.198-1.423), AFP (HR=1.784, 95% CI: 1.366-2.164), Differentiation (HR=1.664, 95% CI: 1.287-2.102), MVI (HR=2.172, 95% CI: 1.618-2.914), PVTT (HR=1.899, 95% CI: 1.573-2.223), and CSPH (HR=1.428, 95% CI: 1.132-1.921) were risk factors affecting patient OS. The gene discussed is AFP; the disease is neoplasm.