A set of genes associated with the extracellular matrix-receptor interaction pathway, which include ITGA5 (integrin alpha five subunits), ITGB1 (integrin beta 1 subunit), LAMB1 (laminin beta 1 subunit), and LAMC1 (laminin gamma 1 subunit), are overexpressed in HPV-positive HNCs (and cervical cancers). The gene discussed is LAMB1; the disease is cervical cancer.