Peli1 is a novel regulator of TNF and TLR signaling in human myometrial and amniotic cells and upregulates the expression of pro-inflammatory factors, adhesion factors, and contractile proteinsPeli1 upregulation in the amniotic membranes of patients with preterm histological chorioamnionitis suggests its potential as a therapeutic target for reducing preterm delivery caused by inflammation and infection (155). This evidence concerns the gene PELI1 and infection.