MiRNAs have been explored as regulators of Peli1 and human umbilical cord mesenchymal stem cell-derived extracellular vesicles modified with miR-30c-5p effectively suppress Peli1 expression and inhibit papillary thyroid carcinoma progression in vitro and in vivo (103). Here, PELI1 is linked to thyroid gland papillary carcinoma.