In summary, we identified 13 ferroptosis-related genes (DRD5, TSC22D3, TFAP2A, STMN1, DDIT3, MYCN, ELAVL1, JUN, DUSP1, MIB1, PSAT1, LCE2C, and MIR27A) as the target genes induced by CPAP therapy (1 year) in the patient with OSA. Here, DUSP1 is linked to obstructive sleep apnea syndrome.