Finally, we screened 13 ferroptosis-related genes (DRD5, TSC22D3, TFAP2A, STMN1, DDIT3, MYCN, ELAVL1, JUN, DUSP1, MIB1, PSAT1, LCE2C, and MIR27A) as potential targets for improving OSA with CPAP. Here, TSC22D3 is linked to obstructive sleep apnea syndrome.