Oxidative stress is widely present in Alzheimer’s disease (AD), and transplantation of human placenta amniotic membrane-derived mesenchymal stem cells (hAMMSCs) into C57BL/6J-APP transgenic mice can reduce lipid peroxidation and oxidative stress levels and increase antioxidant enzyme levels to ameliorate the oxidative stress damage characteristic of AD (Jiao et al., 2016). This evidence concerns the gene APP and Alzheimer disease.