Similar to clinically reported human patients with TRAF7 variants presenting with neurodevelopmental disorders, Tg(huC:RFP) zebrafish injected with traf7 ATG-MO showed significantly reduced huC fluorescent signals compared to the uninjected and control-MO groups (Figure 2D and E), suggesting fewer neurons projecting or excessive neural cell death during zebrafish development. Here, TRAF7 is linked to neurodevelopmental disorder.