IFNG and multiple sclerosis: Furthermore, the Eubacteriales genus Dorea, which was reported to be increased in multiple sclerosis patients, was demonstrated to include species that promote inflammation by triggering IFN-γ production and to potentially enhance intestinal permeability by degrading mucin and metabolizing sialic acids.38,39 In addition, Coriobacteriaceae, Blautia spp., and C. aerofaciens were all enhanced in overweight/obese subjects.40 In addition, the authors of this study reported a positive association of Dorea spp.