We examined the expression of ferroptosis and pyroptosis‐associated proteins in HepG2 cancer cells after treatment with pyroptosis inducers and the apoptosis trigger vincristine (VCR), and found that the expression of HMGCR, GPX4, cleaved caspase1 and GSDMD‐N was significantly upregulated after treatment with pyroptosis inducers, but not after treatment with the apoptosis trigger VCR (Figure S1N, Supporting Information). Here, GPX4 is linked to cancer.