Compared with the low NPAR group, the middle and high NPAR groups were associated with an increased risk of all-cause mortality in PD patients (HR: 4.5, 95%; CI: 3.1–6.4, p < 0.001), and this result remained statistically significant after adjusting for other cofounders (Model 4, HR: 3.1, 95%; CI: 2.1–4.6, p < 0.001), including age, sex, hypertension, diabetes, cardiovascular disease, hemoglobin, platelets, serum creatinine, phosphorus, low density lipoprotein and C-reactive protein (Table 2). The gene discussed is CRP; the disease is hypertensive disorder.