By regulating the expression of CALCRL, MYO3B, DNASE1, FGF20, and other genes, they can inhibit intercellular signal transduction, transcription and replication processes to resist virus invasion and cell apoptosis after infection, and exert the immune response effect of interferon effector genes such as MX1, IFIT2, and CCL15. The gene discussed is IFIT2; the disease is infection.