FOXN4, a member of the forkhead box/winged-helix transcription factor superfamily, is an important transcriptional regulatory gene and significantly overexpressed in EBV-positive nasopharyngeal carcinoma (NPC), promoting EBVs replication and cells tumorigenesis [78]; KLK1 is a widely distributed serine protease, and it has been shown that the levels of KLK1 increased, in the lungs ofmice during influenza virus infection. This evidence concerns the gene FOXN4 and nasopharyngeal carcinoma.