AD-derived astrocytes showed a significantly elevated secretion of IL-6 compared to healthy controls after exposure to both 5 μM (963.2 ± 697.6 SD and 130.0 ± 85.9 SD, respectively) (p < 0.01) and 10 μM Aβ42 (1023.0 pg/mL ± 621.7 SD and 118.8 pg/mL ± 90.9 SD, respectively) (p < 0.001; Fig. 7A). The gene discussed is IL6; the disease is Alzheimer disease.