These mutations are also present in Tfh-type PTCL, with the exception of the IDH2R172 mutation, which is strongly associated with AITL labeling and correlates with specific pathological manifestations, and the SYK fusion, which is more frequently detected in follicular PTCL [45, 46]. The gene discussed is SYK; the disease is mature T-cell and NK-cell non-Hodgkin lymphoma.