MIF and Alzheimer disease: As shown in Fig. 3, macrophage migration inhibitory factor (MIF) (OR = 1.322, 95%CI = 1.141 ~ 1.532, P < 0.001) and basic fibroblast growth factor (FGFBasic) (OR = 1.538, 95%CI = 1.202 ~ 1.969, P = 0.001) significantly increased the incidence of AD (Additional file 7: Table S6).