TF and hepatocellular carcinoma: It is worth mentioning that our established 9-TF signature (1-year AUC = 0.792, 2-year AUC = 0.71 and 3-year AUC = 0.695) showed improved predictive capability for the survival rate of HCC patients compared to the previously identified 2-TF signature (1-year AUC = 0.73, 2-year AUC = 0.60 and 3-year AUC = 0.61) based on the TCGA database [15].