BRIP1 and ovarian cancer: FANCJ, also known as BRIP1 (for BRCA1-interacting protein 1) or BACH1 (BRCA1-associated C-terminal helicase 1), belongs to super-family 2 (SF2) Iron–Sulfur (Fe–S) cluster-containing DNA helicases, and is frequently mutated in breast and ovarian cancers, as well as in many other tumor types (Brosh and Cantor, 2014; Cantor et al, 2001).