NBN and infection: Viral DNA replication was increased by 1.67-fold in MOLT-3 cells depleted of NBS1 72 h post-infection compared with control cells (note that this is likely underestimated, as CellTiter-Glo® assays revealed that the shRNA against NBS1 is moderately toxic in MOLT-3 cells (Fig. 8C and Appendix Fig. S8D)).