CD8A and melanoma: Verhoeven and collaborators first observed how the depletion of autophagy-involved genes (such as Atg5, Atg12, and Atg9) in TECs improves the immunosurveillance status in two syngeneic mouse models of melanoma with different degree of immunogenicity by enhancing the ability to attract Granzyme B (GrZB) protease expressing CD8+ T-cells that infiltrate and restrain tumor growth.