BCL2L1 and neoplasm: To assess if part of the effects of Bcl-xL blockade on tumor progression are nevertheless neutrophil-independent, we initiated a regimen of neutrophil depletion using daily anti-Ly6G + anti-rat antibodies (Boivin et al, 2020) 2 days before A-1331852 treatment initiation and continued the combination for 2 weeks.