The antibody effects were seen in WARS1-induced gene profiling mirrors of hyperinflammatory sepsis endotypes, such as Molecular Diagnosis and Risk Stratification of Sepsis (MARS) 2, inflammopathic endotype, and delta-inflammatory status phenotype, which are characterized by the upregulation of genes implicated in cytokine and chemokine signaling, TLRs, and NF-κB activation (Scicluna et al, 2017; Seymour et al, 2017; Sweeney et al, 2018). The gene discussed is WARS1; the disease is Sepsis.