We validated the survival associations of GJB2 and SCN9A expression in two independent GBM cohorts, including 136 samples from the Glioma Longitudinal Analysis (GLASS) (Glass Consortium, 2018) and 55 samples from an earlier microarray dataset (Freije et al, 2004) (Fig. 3B). This evidence concerns the gene GJB2 and central nervous system cancer.