In contrast, p53-null tumors (whether MSS or MSI) showed markedly more peritoneal metastasis (6 of 9, 67% of mice for MSS, and 6 of 10, 60% of mice for MSI, compared to 2 of 9, 22% of mice for GS tumors), whereas MSI tumors showed markedly less lung metastasis (3 of 10, 30% of mice, compared to 5 of 9, 56% of mice for GS and 6 of 9, 67% mice for CIN tumors) (Fig. 5l–n,p–q). Here, TP53 is linked to cervical squamous intraepithelial neoplasia.