The MYC-p53−/− tumors could be detected by palpation and ultrasound imaging (upon reaching a size of ~3 mm) and they developed at the electroporation site through a stepwise progression of precursor lesions (Extended Data Fig. 2b–n) to moderately well-differentiated adenocarcinomas of the intestinal phenotype (Fig. 2b and Extended Data Fig. 3a–i)9. Here, MYC is linked to adenocarcinoma.