ACTA1 and pulmonary fibrosis: As 14 days after bleomycin instillation is the best time point to measure lung fibrosis parameters, we performed the masson’s staining and α-SMA IHC to detect the lung fibrosis in mice lung transfected with shYTHDC1 or control 14 days after BLM treatment and also got the same conclusion (Appendix Fig. S2A–D).