WSB2 was positively associated with large tumor size (p = 0.001), vascular invasion (p = 0.002), distant metastasis (p = 0.016) and advanced TNM stage (p < 0.001) in HCC patients with wild-type TP53 but not mutant TP53 (Supplementary Fig. 4a, b; Supplementary Tables 5, 6). This evidence concerns the gene WSB2 and hepatocellular carcinoma.