As a result of the STRING analysis, the proteins associated with CHI3L1 in lung cancer were identified in the order of VEGFA, TNF Receptor Superfamily Member 10a (TNFRSF10A), IL-13Rα2, chitinase-domain-containing 1 (CHID), IL-13, Transmembrane Protein 219 (TMEM219), IL-6, and C-reactive protein (CRP) (Fig. 4a upper panel). Here, TMEM219 is linked to lung cancer.