TOMM40 and Parkinson disease: Other GWAS confirmed the association with mutations in GBA and APOE in PD11,26 and Lewy body dementia (LBD)27, and reported genome-wide significant associations with Apolipoprotein C1 (APOC1), translocase of outer mitochondrial membrane 40 (TOMM40), the regulating synaptic membrane exocytosis 2 (RIMS2) genes, as well as suggestive associations in transmembrane protein 108 (TMEM108) and WW domain-containing oxidoreductase (WWOX) genes in PD, but with limited effect sizes11,26.