Taken together, our comprehensive transcriptomic analysis identified BLK and LCK as (1) upregulated in sphere versus adherent culture, (2) more highly expressed in recurrent versus primary DSRCT tumor samples, (3) positively regulated by the EWSR1-WT1 fusion gene, and (4) highly expressed in DSRCT as compared to other tumor types. The gene discussed is EWSR1; the disease is neoplasm.