Similarly, flow cytometry showed that the percentages and counts of neutrophils and AMs, and the levels of hallmark cytokines of neutrophilic inflammation were markedly increased in LysMCreCul5fl/fl asthma exacerbation mice administered with IFN-β-neutralizing antibody compared with Isotype controls (Fig. 3h–k). The gene discussed is IFNB1; the disease is asthma.