Moreover, our data showed a stronger therapeutic effect of IFN-β than that of Dex in asthma exacerbation mice by reducing histological injury, inflammatory cell infiltration, influenza replication, serum IgE levels, the percentage and count of neutrophils, and the expression of neutrophilic inflammatory genes (Fig. 8d–k and Supplementary Fig. 14). This evidence concerns the gene IFNB1 and influenza.