Notably, KRAS mutant cases with high POM121 protein positivity had more PPARγ protein localized to the peri-nuclear and cytoplasmic regions of the tumor cells compared with KRAS wt cases, who showed nuclear positivity of PPARγ (n = 208, *p < 0.05, Fisher Exact test) (Fig. 1F). This evidence concerns the gene PPARG and neoplasm.