Studies have shown that NLRP3 levels are higher in ovarian endometriosis samples, and using MCC950 to inhibit NLRP3 has been shown to decrease IL-1β concentrations in cyst-derived stromal cells.334 The results suggested that NLRP3/IL-1β is crucial for the pathogenesis of endometriosis. The gene discussed is NLRP3; the disease is cyst.