MAPK1 and neoplasm: In breast cancer, circDNAJC11 promotes cell proliferation and tumor progression by interacting with TAF15 to upregulate MAPK6 expression and activate the MAPK signaling [201]; circBACH2 (hsa_circ_0001625) promotes cell proliferation via regulating hsa-miR-944/HNRNPC axis and stimulating MAPK signaling pathway [202]; hsa_circRNA_0006528 (circ_0006528) promotes proliferation and growth phenotypes by sponging miR-7-5p to enhance Raf1 expression and then activating the MAPK/ERK signaling pathway [203].